Deprecated: Required parameter $cat_id follows optional parameter $type in /www/wwwroot/ebimall.com/systems/hong.php on line 2088

Deprecated: Required parameter $where follows optional parameter $tree_id in /www/wwwroot/ebimall.com/systems/hlb.php on line 3505
Hello Bio/ML7 hydrochloride/HB0415/25mg188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
您好,欢迎您进入188进口试剂采购网网站! 服务热线:4000-520-616
蚂蚁淘商城 | 现货促销 | 科研狗 | 生物在线

Hello Bio/ML7 hydrochloride/HB0415/25mg

Product overview

  • Name
    ML-7 hydrochloride
  • Short description
    Selective MLCK inhibitor
  • Biological description
    Selective myosin light chain kinase (MLCK) inhibitor (Ki = 0.3 µM). Shows reversible ATP- competitive inhibition of Ca2+ calmodulin independent/ dependant smooth muscle MLCK. Approx 10-fold more potent inhibitor than ML-9 Shows antiglaucomatous actions.
  • Biological action
    Inhibitor
  • Purity
    >99%
  • Our products in action
    Submit Your Citation Now

Properties

  • Chemical name
    Hexahydro-1-[(5-iodo-1-naphthalenyl)sulfonyl]-1H-1,4-diazepine hydrochloride
  • Molecular Weight
    452.74
  • Chemical structure
    ML-7 [110448-33-4]
  • Molecular Formula
    C15H17IN2O2S.HCl
  • CAS Number
    110448-33-4
  • PubChem identifier
    9803932
  • SMILES
    C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CC=C3I.Cl

Storing and Using Your Product

  • Storage instructions
    room temperature (desiccate)
  • Solubility overview
    soluble in DMSO (25mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for ML-7 hydrochloride

  • Selective inhibition of catalytic activity of smooth muscle myosin light chain kinase.

    Saitoh M et al (1987)J Biol Chem 262(16) : 7796-801.
    PubMedID: 3108259

  • The specificities of protein kinase inhibitors: an update.

    Bain J et al (2003)Biochem J 371(Pt 1) : 199-204.
    PubMedID: 12534346

  • Effects of ML-7 and Y-27632 on carbachol- and endothelin-1-induced contraction of bovine trabecular meshwork.

    Rosenthal R et al (2005)Exp Eye Res 80(6) : 837-45.
    PubMedID: 15939040

新闻动态
行业前沿
技术文章
最新产品

188进口试剂采购网 www.188bio.cn -中国试剂网,试剂网,化学试剂网,国药试剂,抗体公司,试剂公司,试剂盒公司,苏州试剂公司,北京化学试剂公司,天津化学试剂,试剂商城,试剂代理,流式抗体 细胞库查询 sitemap