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Hello Bio/cAMPSRp, triethylammonium salt/HB0165/1mg

Product overview

  • Name
    cAMPS-Rp, triethylammonium salt
  • Short description
    cAMP antagonist
  • Biological description
    cAMP analog. Antagonises cAMP cell surface receptor, type I and II protein kinases. Competitive antagonist of c-AMP-induced PKA activation (IC50. Inhibits pain-related synaptic plasticity in amygdala brain tissue. Cell permeable.
  • Biological action
    Antagonist
  • Purity
    >98%
  • Our products in action
    Submit Your Citation Now

Properties

  • Chemical name
    (R)-Adenosine,cyclic3,5-(hydrogenphosphorothioate)triethylammonium
  • Molecular Weight
    446.46
  • Molecular Formula
    C10H12N5O5PS.C6H15N
  • CAS Number
    151837-09-1

Storing and Using Your Product

  • Storage instructions
    -20°C (desiccate)
  • Solubility overview
    soluble in water (100mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for cAMPS-Rp, triethylammonium salt

  • PKA and ERK, but not PKC, in the amygdala contribute to pain-related synaptic plasticity and behavior.

    Fu Y et al (2008)Mol Pain 4 : 26
    PubMedID: 18631385

  • Probing the cyclic nucleotide binding sites of cAMP-dependent protein kinases I and II with analogs of adenosine 3,5-cyclic phosphorothioates.

    Dostmann WR et al (1990)J Biol Chem 265(18) : 10484-91.
    PubMedID: 2162349

  • Competitive cAMP antagonists for cAMP-receptor proteins.

    Van Haastert PJ et al (1984)J Biol Chem 259(16) : 10020-4.
    PubMedID: 6088478

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