QED Bioscience/Recombinant CCL14 (HCC1)/50192P10/1 Ea

CatalogNo.Size

50192P-22ug

50192P-1010ug

50192P-5050ug

50192P-100100ug

50192P-10001000ug

CCL14,alsoknownasHemofiltrateCCChemokine-1(HCC-1)isasmallcytokine(~8kDa)thatisconstitutivelyexpressedinmultipletissues.UponprocessingoftheN-terminalresiduesoffull-lengthHCC-1bytheuPA-plasminsystem,theactiveformofHCC-1isastrongagonistforCCR1,CCR5,and,toalesserextent,CCR3.CCL14causeschemotaxisofdifferenttypesofleukocytes,anditsactiveformisapotentinhibitorofHIVentry.

Source:RecombinanthumanCCL14isproducedinE.coli(accessionno.

Q16627,aa28-93).

ProteinSequence:GPYHPSECCFTYTTYKIPRQRIMDYYETNSQCSKPGIVFITKRGHSVCTNPSDKWVQDYIKDMKEN

MolecularMass:7.801kDabyMassSpec.

Purity:>97%bySDS-PAGE

Activity:EC50=0.1-0.4nMdeterminedbyMigrationAssayincellsexpressingCCR1.

EndotoxinLevel:<0.01EUper1ugofproteinbyLALmethod.

Form:Lyophilized.

CarrierProtein:None.

Reconstitution:Recommendedat100ug/mlinsteriledistilledwater.

StabilityandStorage:12monthsfromdateofreceipt,-20oCto-70oC,assupplied.

1month,-20oCto-70oC,understerileconditionsafterreconstitution.Bestifusedimmediatelyafterreconstitution.

Avoidmultiplefreeze-thawcycles.

Forinvitroinvestigationaluseonly.Notforuseindiagnosticortherapeuticprocedures.