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QED Bioscience/Recombinant Human CCL27 (CTACK)/50182P1000/1 Ea


RecombinantCCL27(CTACK)



ORDERINGINFORMATIONORDERINGINFORMATION

CatalogNo.Size

50182P-22ug

50182P-1010ug

50182P-5050ug

50182P-100100ug

50182P-10001000ug


BACKGROUNDBACKGROUND

CCL27,alsoknownasCutaneousT-cell-attractingChemokine(CTACK)isaligandforcellsurfacereceptorCCR10.Itisresponsibleforchemotaxisofskin-homingmemoryT-cellsduringcutaneousinflammation.Interestingly,afterCCR10-mediatedinternalization,CCL27,aswellasanon-secretedsplicevariantofthesamegene,canreachthenucleusandmodulatetranscriptionandcellbehavior.

DESCRIPTIONDESCRIPTION

Source:RecombinanthumanCCL27,producedinE.coli,correspondstoaa25-112(accessionno.Q9Y4X3).

ProteinSequence:FLLPPSTACCTQLYRKPLSDKLLRKVIQVELQEADGDCHLQAFVLHLAQRSICIHPQNPSLSQWFEHQERKLHGTLPKLNFGMLRKMG

MolecularMass:10.149kDabyMassSpec.

Purity:>97%

Activity:EC50=34nMdeterminedbyMigrationAssayinL1.2cellsexpressingCCR10.

EndotoxinLevel:<0.01EUper1ugofproteinbyLALmethod.

Form:Lyophilized.

CarrierProtein:None.


PREPARATIONANDSTORAGEPREPARATIONANDSTORAGE

Reconstitution:Recommendedat100ug/mlinsteriledistilledwater.

StabilityandStorage:12monthsfromdateofreceipt,-20oCto-70oC,assupplied.

1month,2oCto8oC,understerileconditionsafterreconstitution.

3months,-20oCto-70oC,understerileconditionsafterreconstitution.


Forinvitroinvestigationaluseonly.Notforuseindiagnosticortherapeuticprocedures.


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