QED Bioscience/AnkyrinB/56518/1 Ea

CatalogNo.:56518(cloneS105-13)Size:100uginPBS(1mg/ml),pH7.4,50%glycerol,0.09%sodiumazide.

PurifiedbyProteinGaffinitychromatography.

Ankyrinsareafamilyofadaptorproteinsthatmediatetheattachmentofintegralmembraneproteinstothespectrin-actinbasedmembraneskeleton.Ankyrinshavebindingsitesforthebetasubunitofspectrinandforatleast12familiesofintegralmembraneproteins.Thislinkageisrequiredtomaintaintheintegrityoftheplasmamembranesandtoanchorspecificionchannels,ionexchangers,andiontransportersintheplasmamembrane.

Antigen:Syntheticpeptidecorrespond-ingtoaa203-496ofhumanAnkyrin-B(accessionno.NP_001120965.1)

HostSpecies:Mouse

AntibodyClass:IgG1

Thisantibodyrecognizeshuman,mouse,andratAnkyrin-B.

Immunoblotting:useat1-2ug/ml.Abandof>200kDaisdetected.

Immunoblotonmouse(M)andrat(R)brainmembranes.

Immunohistochemistry:useat1-5ug/ml.Thesearerecommendedconcentrations.

Endusershoulddetermineoptimalconcentrationsfortheirapplications.Positivecontrol:ratbrainmembranes.

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

Thisproductisstableforatleast1yearat

-20oC.Freezeinmultiplealiquotstoavoidrepeatedfreeze-thawcycles.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.