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QED Bioscience/Syntaxin/56479/1 Ea

QEDBioscienceInc.

ADVANCEDRESEARCHTECHNOLOGIES

Anti-SyntaxinMonoclonalAntibody

ORDERINGINFORMATION

CatalogNo.:56479(cloneSP6)Size:100uginPBS,pH7.4;50%

glycerol,0.09%sodiumazide.PurifiedbyProteinGaffinitychromatography.

BACKGROUND

Syntaxinisa~38kDatypeIIintegralmembraneproteinlocalizedtotheplasmamembraneatnerveterminals.SyntaxinwasidentifiedthroughitsassociationwithsynaptotagminandN-typecalciumchannel,asubtypeofcalciumchannelontheplasmamembranethatisimportantforneurotransmitterrelease.Homologsofsyntaxinhavebeenidentifiedinvariouseukaryotesrangingfromyeasttohuman.SyntaxinisalsothetargetofclostridialneurotoxinC1thatblocksneurotransmitterrelease.

SPECIFICATIONSUMMARY

Antigen:Synapticvesicle-containingfractionspurifiedfromhumanbrainextracts.

HostSpecies:Mouse

AntibodyClass:IgG1

SPECIFICITY

Thisantibodyrecognizeshuman,mouse,rat,hamster,bovine,feline,andporcinesyntaxin.

APPLICATIONS

Immunoblotting:useat1-10ug/ml.Abandof~38kDaisdetected.

Thesearerecommendedconcentrations.Usershoulddetermineoptimalconcentrationsfortheirapplication.

Positivecontrol:Ratbrainlysate.

DILUTIONINSTRUCTIONS

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

STORAGEANDSTABILITY

Thisantibodyisstableforatleastone(1)yearat-20oC.Avoidrepeatedfreezingandthawing.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.

10919TechnologyPlace,SuiteCSanDiego,California92127Tel800-929-2114/858-675-2405Fax858-592-1509

Emailinfo@qedbio.comwww.qedbio.com

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