QED Bioscience/BRCA2/3303/1 Ea

productdatasheet

CatalogNo.:3303

Size:100ugProteinG-purifiedantibodyinPBS,pH7.4

Antigen:GSTfusionproteinexpressedinE.colicorrespondingtoaa2336-2478ofhumanBRCA2.

HostSpecies:MouseAntibodyClass:IgG1/κStabilizers:None

Preservatives:None.Availableonrequest.

ThisantibodyrecognizeshumanBRCA2,a390kDnuclearprotein.BRCA2hasbeenassociatedwithpredispositionofwomentoearly-onsetbreastandovariancancers.BRCA2appearstobeinvolvedinDNArecombinationanddoublestrandbreakrepair.

Immunoblotting:useat1-5ug/ml.

Positivecontrol:Molt4cells.

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

Thisantibodyisstableforatleastone

(1)yearat-70oC.Avoidmultiplefreeze-thawcycles.

Chen,P-Letal.1998.PNAS(USA)95:5287-5292.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.

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