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Lunginnov/Dermatan sulfate chains from recombinant human endocan/LIDS-50U

Description:

Endocanisaproteoglycancomposedofa20kDamaturepolypeptideanda30kDachondroitin/ dermatansulfatechain.

PurifiedrecombinanthumanEndocan(LIP-1001)istreatedwithproteinaseK.Thentheglycanchainis purifiedbyionexchangeonDEAE-sepharose

KeyidentifiedBIOLOGicalactivities:

  • increasesendothelialmigrationinducedbyVEGF,
  • comitogenwithHGF/SFandFGF-2.

Characteristics:

  • Purifiedbyionexchangechromatography
  • PM:30kDapolyacrylamidegelrevealedbyAlcianblue
  • Format:50µg
  • Whenstoredat-80°Cinphosphatebufferwithoutpreservatives
  • Applications:bioassays
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