下一代固相染色质免疫沉淀（ChIP）分析技术 — Chromatrap®染色质免疫沉淀（ChIP）系列

Chromatrap®使用Porvair Sciences专利过滤器，与英国斯旺西大学的生殖生物学和妇科肿瘤组合作开发出更灵敏的染色质免疫沉淀技术。特别适合于微量或低丰度生物样品。
Chromatrap® ChIP采用与蛋白质A或G结合的固相多孔聚合物来捕获染色质、Chromatrap®试剂盒（专利号：GB2482209）采用与蛋白质A 结合的固相多孔聚合物来捕获染色质，较磁珠法的效率得以极大提高。过去的琼脂糖珠或磁珠法工艺复杂，涉及分离、移液和再悬浮等操作，相比之下，Chromatrap 离心柱法的优势显得尤为突出。
独立实验表明，Chromatrap 法比传统珠式工艺的 DNA Pull Down 水平高出 25 倍，DNA 富集的信噪比尤为显著，要比常见的工艺高出 2 至3 倍，即使沉淀反应的用品用量过少至 50ng 或过多至 3000ng，都能得出十分稳定的结果。
Chromatrap® ChIP简化qPCR分析流程 5小时内制备染色质

Epigenetics Researchers Enthuse Over Chromatrap® ChIP technology
1. Brian J. Engel, a Biochemistry & Cell Biology researcher at Rice University, USA commented "What I like most about the Chromatrap kit compared to traditional bead-based ChIP assays is the ease of use, speed and reliability. There is no worry about accidentally losing beads during washes and reducing output chromatin when using the column-based method". His colleague - Curt Warren added "We have found that the Chromatrap kit is quick, reliable and flexible. Saving reagents and time with this kit makes it easier and more feasible to conduct more thorough and effective IP based experiments. With the enhanced reproducibility using Chromatrap, I would not go back to bead-based ChIP and the assay has been fully endorsed and adopted within our research team".

2. Professor Steve Conlan, Head of Molecular & Cell Biology at Swansea University, UK commented "Chromatrap streamlines the complicated experimental procedure associated with chromatin-IP making it a much quicker and user-friendly assay compared to conventional bead based assays. Using this kit we obtain much more consistent data, and most importantly can use much less input sample. We have made a permanent switch to using Chromatrap for all our cell line and primary cell based assays, and fully endorse the technology". Research assistant - Dr Helen Whiteland added "What I like about the Chromatrap assay is the ease of use and quick method allowing me to analyse my data in the same day".