Signosis/TF Activation Profiling Plate Array III/FA1011/1 Ea

Description:

Transcriptionfactors(TFs)areagroupofcellularproteinsthatplayessentialrolesinregulatinggeneexpression.Theyactassensorstomonitorcellularchangeandconvertthesignalsintoalteredgeneexpression.Often,aspecificcellularsignalpathwaycanactivatemultipleTFsandtheexpressionofaspecificgeneisundercontrolofmultipleTFs.Hence,monitoringtheactivationofmultipleTFssimultaneouslyiscriticaltounderstandthemolecularmechanismofcellularregulationunderlyingcellsignalingandgeneexpression.Signosis’TFactivationprofilingplatearrayIIIFA-1011isusedformonitoring48differentTFsincludingATF6,CHOP,Nanog,andSREBP1.

ApplicableGrid:

 

ListofApplicableTFs:

1

2

3

4

5

6

7

8

9

10

11

12

A

AHR

Evl-1

INSM2

MNF1

PITX2

SREBP1

AHR

Evl-1

INSM1

MNF1

PITX2

SREBP1

B

ATF3

FXR

ISGF

MTF

PRDM14

TBET

ATF3

FXR

ISGF

MTF

PRDM14

TBET

C

ATF6

GBX2

KRF1

Nanog

PROP1

TBX3

ATF6

GBX2

KRF1

Nanog

PROP1

TBX3

D

CHOP

GKLF

LRH-1

Nhlh1 (HEN)

pu.1

Tead

CHOP

GKLF

LRH-1

Nhlh1 (HEN)

pu.1

Tead

E

E12/E47

HES1

LXR

Notch

REST

TFEB

E12/E47

HES1

LXR

Notch

REST

TFEB

F

EBF1

HFH1

MAF

NUR77

RREB

TGIF/Meis2

EBF1

HFH1

MAF

NUR77

RREB

TGIF/Meis2

G

EBP-80

HLF

MIBP

OLIG1

SIX

Twist1

EBP-80

HLF

MIBP

OLIG1

SIX

Twist1

H

EKLF

HOXA4

MITF

PEA3/EVT4

Sperm1

VAX2

EKLF

HOXA4

MITF

PEA3/EVT4

Sperm1

VAX2