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Signosis/TF Activation Profiling Plate Array III with Nuclear Extraction Kit/FA-1011-NE/1 Ea

Description:

Transcriptionfactors(TFs)areagroupofcellularproteinsthatplayessentialrolesinregulatinggeneexpression.Theyactassensorstomonitorcellularchangeandconvertthesignalsintoalteredgeneexpression.Often,aspecificcellularsignalpathwaycanactivatemultipleTFsandtheexpressionofaspecificgeneisundercontrolofmultipleTFs.Hence,monitoringtheactivationofmultipleTFssimultaneouslyiscriticaltounderstandthemolecularmechanismofcellularregulationunderlyingcellsignalingandgeneexpression.Signosis’TFactivationprofilingplatearrayIIIFA-1011isusedformonitoring 48differentTFs includingATF6,CHOP,Nanog,andSREBP1.

ApplicableGrid:

ListofApplicableTFs:

 123

4

5

6

78910

11

12
AAHREvl-1INSM2MNF1PITX2SREBP1AHREvl-1INSM1MNF1PITX2SREBP1
BATF3 FXR ISGFMTFPRDM14TBETATF3FXRISGFMTFPRDM14TBET
CATF6GBX2KRF1NanogPROP1TBX3ATF6GBX2KRF1NanogPROP1TBX3
DCHOPGKLFLRH-1Nhlh1
(HEN) 
pu.1TeadCHOPGKLFLRH-1Nhlh1
(HEN) 
pu.1Tead
EE12/E47HES1LXRNotchRESTTFEBE12/E47HES1LXRNotchRESTTFEB
FEBF1HFH1MAFNUR77 RREBTGIF/Meis2EBF1HFH1MAFNUR77RREBTGIF/Meis2 
GEBP-80HLFMIBPOLIG1SIXTwist1EBP-80HLFMIBPOLIG1SIXTwist1
HEKLFHOXA4MITFPEA3/EVT4      Sperm1VAX2EKLFHOXA4MITFPEA3/EVT4Sperm1VAX2
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