MedKoo Biosciences/Estriol/315241/2g

Synonym:oestriol.

IUPAC/ChemicalName:(8R,9S,13S,14S,16R,17R)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,16,17-triol

InChiKey:PROQIPRRNZUXQM-ZXXIGWHRSA-N

InChiCode:InChI=1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h4,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16-,17+,18+/m1/s1

SMILESCode:OC1=CC=C2[C@@]3([H])CC[C@]4(C)[C@@H](O)[C@H](O)C[C@@]4([H])[C@]3([H])CCC2=C1

TechnicalData

References

1:DondersG,BellenG,NevenP,GrobP,PrasauskasV,BuchholzS,OrtmannO.Effectofultra-low-doseestriolandlactobacillivaginaltablets(Gynoflor®)oninflammatoryandinfectiousMarkersofthevaginalecosysteminpostmenopausalwomenwithbreastcanceronaromataseinhibitors.EurJClinMicrobiolInfectDis.2015Jul30.[Epubaheadofprint]PubMedPMID:26223323.

2:CarusoS,CianciS,AmoreFF,VenturaB,BambiliE,SpadolaS,CianciA.Qualityoflifeandsexualfunctionofnaturallypostmenopausalwomenonanultralow-concentrationestriolvaginalgel.Menopause.2015Jun15.[Epubaheadofprint]PubMedPMID:26079974.

3:CastellaniD,SalduttoP,GalicaV,PaceG,BiferiD,ParadisoGalatiotoG,VicentiniC.Low-DoseIntravaginalEstriolandPelvicFloorRehABIlitationinPost-MenopausalStressUrinaryIncontinence.UrolInt.2015May30.[Epubaheadofprint]PubMedPMID:26043913.

4:SoghraK,ZohrehS,KobraAK,RezaMM.Singlemeasurementofsalivaryestriolasapredictorofpretermbirth.PakJBiolSci.2014May;17(5):730-4.PubMedPMID:26031009.

5:TomiM,EguchiH,OzakiM,TawaraT,NishimuraS,HiguchiK,MaruyamaT,NishimuraT,NakashimaE.RoleofOAT4inUptakeofEstriolPrecursor16α-HydroxydehydroepiandrosteroneSulfateIntoHumanPlacentalSyncytiotrophoblastsFromFetus.Endocrinology.2015Jul;156(7):2704-12.doi:10.1210/en.2015-1130.Epub2015Apr28.PubMedPMID:25919187.

6:DurkovićJ,MilenkovićT,KroneN,ParajesS,MandićB.LowestriollevelsinthematernalmarkerscreenasapredictorofX-linkedadrenalhypoplasiacongenita:casereport.SrpArhCelokLek.2014Nov-Dec;142(11-12):728-31.PubMedPMID:25731006.

7:LiuZH,LuGN,YinH,DangZ.Doweunderestimatetheconcentrationofestriolinrawmunicipalwastewater?EnvironSciPollutResInt.2015Mar;22(6):4753-8.doi:10.1007/s11356-014-3981-6.Epub2014Dec24.PubMedPMID:25537286.

8:ShirshevSV,MaslennikovaIL,NekrasovaIV.[EffectofEscherichiacolisecretedmetabolitesonfunctionalactivityofhumanneutrophilsagainstthebackgroundofestrioleffect].ZhMikrobiolEpidemiolImmunobiol.2014Sep-Oct;(5):65-70.Russian.PubMedPMID:25536774.

9:YamabeN,KangKS,LeeW,KimSN,ZhuBT.Estriolbluntspostprandialbloodglucoseriseinmaleratsthroughregulatingintestinalglucosetransporters.AmJPhysiolEndocrinolMetab.2015Mar1;308(5):E370-9.doi:10.1152/ajpendo.00209.2013.Epub2014Dec16.PubMedPMID:25516546;PubMedCentralPMCID:PMC4346740.

10:GirgertR,EmonsG,GründkerC.InhibitionofGPR30byestriolpreventsgrowthstimulationoftriple-negativebreastcancercellsby17β-estradiol.BMCCancer.2014Dec11;14:935.doi:10.1186/1471-2407-14-935.PubMedPMID:25496649;PubMedCentralPMCID:PMC4364648.