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Microspheres-Nanospheres/166Ho radionuclide incorporated/100501-21/900nm-500

ThissectionofCatalogdescribestheNuc-SpheretmproductsfromCorpuscular.Theseproprietarymaterialsandtheirmethodsofpreparationandusingarepatentpending.

ThemonodispersenanosphereandmicrosphereparticlesrADIonuclide-carriersareforresearchpurposesonly.

WeoffervariousCorediameterandcoatingthickness"cold"nanosphereswhichuponirradiationinnuclearreactorproducehighlyconcentratedradionuclideconcentrationusefulfordiagnosticandtherapeuticstudies.

SilicasurfacesareeasilyfunctionalizedwithOH,NH2andCOOHgroups,usedtoconjugatetoantibodies. 

NuP-Spheretmproductswillbesoldonlytocustomerswithvalidlicensesforworkwithradioactivematerialsfromauthorizedgovernmentandstateagenciesofrespectivecountries.

 

PropertiesofHolmium-166 radionuclide

 Ebeta(max.)=1.85MeV

 β5-=651.9keV(47.7%abundance)and

 β6-=694.6keV(51.0%abundance)

Softtissuepenetration-average3.2mm,depositing0.2keV/mm.ThetotalequilibriumdoseconstantsDnpandDpfornon-penetratingandpenetratingradiationsof166-Hoare0.398gGyMbq-1h-1and0.017gGyMbq-1h-1,respectively.

166-Hotherapeuticradiusis~2.1mm,andthemaximumradiusis~8.7mm).

Half-lifeof26.808h,

Gammaemissionswithsuitableenergiesandabundance:E=0.081MeV(6.2%)andE=1.379MeV(0.95%).

 

 

 

"Cold"Ho2O3coreandSiO2shellnanospheres

 

 

"Hot"nanospheres

Activation:164Ho(n,γ)→166Ho

166Hobetadecaytostable166Erisotope

 

 

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