CatalogNo.:AB0037-500
Price/Unit:EUR450.00
Source:Goat
Quantity/unitsize:1mg
Description:GoatpolyclonaltoCANX(Calnexin)-endoplasmicreticulum(ER)membraneMarker.CANXisamemberofthecalnexinfamilyofmolecularchaperones.Thisproteinisacalcium-binding,ER-associatedproteinthatinteractstransientlywithnewlysynthesizedN-linkedglycoproteins,facilitatingproteinfoldingandassembly.ItmayalsoplayacentralroleinthequalitycontrolofproteinfoldingbyretainingincorrectlyfoldedproteinsubunitswithintheERfordegradation.Alternativenames:Calnexin,CALX,CNX,FLJ26570, histocompatibilitycomplexclassIantigenbindingproteinp88,IP90,majorhistocompatibilitycomplexclassIantigen-bindingproteinp88,MS952,P90antibody.
Form:Polyclonalantibodysuppliedasa500µl(2mg/ml)aliquotinPBS,20%glyceroland0.05%sodiumazide.Thisantibodyisepitope-affinitypurifiedfromgoatantiserum.
Immunogen:Purifiedrecombinantpeptidewithinresidues550aatotheC-terminusofhumanCANXproducedinE.coli.
Specificity:Detectsabandof90kDabyWesternblotinthefollowinghuman(293A,primaryfibroblasts,HaCat,HeLa,HMEC-1,Jurkat,MNT1,U-118,rat(TR-iBRB),mouse(3T3,AtT-20,Hepa,Raw264.7),monkey(COS-7)andcanine(D17)wholecelllysates.
Reactivity:Reactsagainsthuman,rat,mouse,canineandmonkeyproteins.
Usage:Westernblot 1:500-1:5,000Immunofluorescence 1:50-1:500Immunohistochemistry(paraffin) 1:200-1:1,000Immunohistochemistry(frozen) 1:200-1:1,000
Reactivitychart
Sample | WesternBlot | Immuno-fluorescence | Immuno-Histochemistry(p) | Immuno-Histochemistry(f) | human | +++ | +++ | +++ | +++ | mouse | +++ | +++ | +++ | +++ | rat | +++ | +++ | +++ | +++ | canine | +++ | +++ | +++ | +++ | monkey | +++ | +++ | +++ | +++ |
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Storage:Storeat-20Cforlongtermstorage.Storeat2-8Cforuptoonemonth.
Specialinstructions:Avoidfreeze/thawcycles.
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