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Clone GMA-101
Background
Factor IX (FIX) is a vitamin K-dependent zymogen that plays an essential role in the coagulation cascade leading to thrombus formation. In the presence of calcium, activated Factor IX (FIXa) complexes with Factor VIIIa on phospholipid surfaces to create the tenase complex, which converts Factor X to its activated form. Absent or defective FIX is the cause of the X-linked recessive bleeding disorder hemophilia B. GMA-101 binds to FIX and FIXa in ELISA assays.
More Information
Product Datasheet as PDF
Description
- Species Reactivity:Human
- Source:Murine
- Specificity:FIX/FIXa
- Immunogen:Human Factor IX
- Isotype:IgG1
Application
- ELISA:Binds immobilized Human FIX/IXa.
- Immunoblotting:Not recommended for Western blotting.
- Inhibition:Does not prolong plasma clot time in APTT clotting assay.
Data
Antibody References
- B. Cooley et al. (2016). Blood. (128):286-292.
$265.00 – $660.00