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Ontores/LSKL, Inhibitor of Thrombospondin (TSP-1)/5mg/ONP10872188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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Ontores/LSKL, Inhibitor of Thrombospondin (TSP-1)/5mg/ONP10872

BIOLOGICAL INFORMATION
DescriptionThis peptide, derived from the latency-associated peptide, inhibits thrombospondin (TSP-1) activation of TGF-ß; thus preventing the progression of hepatic damage and fibrosis.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10872
CAS No.283609-79-0
NameLSKL, Inhibitor of Thrombospondin (TSP-1)
Chemical NameLSKL,-Inhibitor-of-Thrombospondin-(TSP-1)
Purity≥98%
SynonymsN/A
FormulaC21H41N5O6
Molecular Weight459.58
One Letter CodeLSKL
Three Letter CodeLeu-Ser-Lys-Leu
SMILESCC(C)CC(C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)N)N
InChI KeyYOKXDNNIFSAXBY-QAETUUGQSA-N
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
ShippingIce Pack
Stability≥ 2 years
REFERENCES & CITATIONS
1. Liao F, et al. LSKL peptide alleviates subarachnoid fibrosis and hydrocephalus by inhibiting TSP1-mediated TGF-β1 signaling activity following subarachnoid hemorrhage in rats. Exp Ther Med. 2016 Oct;12(4):2537-2543. Epub 2016 Aug 31.
2.Laurent MA, et al. In silico characterization of the interaction between LSKL peptide, a LAP-TGF-beta derived peptide, and ADAMTS1. Comput Biol Chem. 2016 Apr;61:155-61.
3.Kuroki H, et al. Effect of LSKL peptide on thrombospondin 1-mediated transforming growth factor β signal activation and liver regeneration after hepatectomy in an experimental model. Br J Surg. 2015 Jun;102(7):813-25.
DOCUMENTATIONS
  • COA
  • Data sheet
  • MS
  • RP-HPLC
  • MSDS
  • Handling Instruction
PROMOTIONS & EVENTS
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