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ViennaLab/Familial Mediterranean Fever (FMF)/20 tests/4-390

Familial Mediterranean Fever (FMF) is characterized by recurrent episodes of fever accompanied by painful inflammatory events. The FMF StripAssays® identify the most frequent disease-causing variants in the MEFV gene and risk factors for amyloidosis.

Familial Mediterranean Fever (FMF)

  • FMF is the most prevalent monogenic autoinflammatory disease mainly affecting people of Mediterranean descent.
  • Mutations in the MEFV gene were found to underlie the development of FMF.
  • A severe long-term complication is systemic AA amyloidosis, which is characterized by extracellular deposition of proteolytic fragments of serum amyloid A (SAA) ultimately leading to organ damage.
  • The homozygous condition of the SAA isotype SAA1.1 is significantly linked to AA amyloidosis and clinical severity in patients with FMF and rheumatoid arthritis.

ProductREFUnit SizeIFUBrochure
FMF StripAssay®4-23020 tests

PDF

PDF

FMF-SAA1 StripAssay®4-39020 tests

PDF

PDF

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