Type I collagen, a fibrous protein abundant in connective tissues such as the tendon, ligament, dermis and blood vessels, is the major component and the primary determinant of tensile strength of the extracellular matrix (ECM). It is widely used as a thin layer on tissue-culture surfaces to enhance the attachment and proliferation of a variety of cells including endothelial cells, fibroblasts, hepatocytes, and epithelial cells. In addition, collagen I can self-assemble into a 3-D supramolecular gel in vitro, making it an ideal biological scaffold to promote more in vivo-like cellular morphology and function.
Collagen I Cell Culture Surface Coating Kit is used to coat cell culture surface in vitro. It is for research use only. Not for use in animals, humans, or diagnostic procedures.