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axonmedchem/BET BRD4 inhibitor compound II-25/5 mg/Axon 3037

BET BRD4 inhibitor compound II-25

Based on 1 reference(s) in Google Scholar8101

Axon 3037

CAS [1660117-38-3]

MF C25H27N5O2MW 429.51

  • Purity:99%
  • Optical purity:Optically pure
  • Soluble in 0.1N HCl(aq) and DMSO

BET BRD4 inhibitor compound II-25

Description

BET BRD4 inhibitor compound II-25 is a potent BRD4-BD1 inhibitor with an IC50 of 8 nM.

KEYWORDS:BET BRD4 inhibitor compound II-25 | BET inhibitor | BI 894999 | BI894999 | BI-894999 | CAS [1660117-38-3] | Histone | BET (BRD) | Inhibitor | Proteins | AML | Acute myeloid leukemia

  • References
  • Certificates
  • Categories
  • Extra info
H Engelhardt et al. Pyridinones. WO2015022332A1.
  • Certificate of Analysis
  • Material Safety Data Sheet
Cell Signaling & OncologyEpigeneticsBET (BRD)
Potent, selective and orally active BET inhibitor

Chemical name

(S)-2,4-Dimethyl-6-(1-(1-phenylethyl)-6-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[4,5-c]pyridin-2-yl)pyridazin-3(2H)-one

Parent CAS No.

[1660117-38-3]

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