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axonmedchem/A 1070722/5 mg/Axon 1909

A 1070722

Based on 16 reference(s) in Google Scholar91016

Axon 1909

CAS [1384424-80-9]

MF C17H13F3N4O2MW 362.31

  • Purity:99%
  • Soluble in DMSO

A 1070722

Description

Potent and selective glycogen synthase kinase GSK-3 inhibitor (Ki=6 nM). Brain penetrating and centrally active GSK-3 inhibitor for the treatment of psychiatric and neurodegenerative disorders
  • References
  • Certificates
  • Categories
  • Extra info
MHM Bakker et al. A-1070722, a potent, selective, and centrally active glycogen synthase kinase-3 (GSK-3) inhibitor for the treatment of psychiatric and neurodegenerative disorders. Society for Neuroscience 2011, Abstract 568.04.
  • Certificate of Analysis
  • Material Safety Data Sheet
Cell Signaling & OncologyCNSDiabetes & MetabolismImmunologyPain & InflammationStem CellGSK-3Wnt-β-CateninPI3K-Akt-mTOREC 2.7.11.26
Selective inhibitor of GSK-3

Chemical name

1-(7-methoxyquinolin-4-yl)-3-(6-(trifluoromethyl)pyridin-2-yl)urea

Parent CAS No.

[1384424-80-9]

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