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MACS/CD90.2 MicroBeads, mouse/130-049-101/

Capacity:for2×109totalcells

Overview

CD90.2MicroBeadsweredevelopedforpositiveselectionordepletionofmouseTcellsfromsingle-cellsUSPensionsoflymphoidandnon-lymphoidtissuesorfromperipheralblood.

Details

Backgroundinformation

ThemouseCD90.2alloantigen,alsoknownasThy1.2,isapanTcellMarkerforthemostcommoninbredmousestrains.ThesestrainsincludeBALB/c,DBA,CBA/J,C3H,C57BL/6,NZB/-,S3Landothers.CD90.2isexpressedonthymocytes,peripheralTcells,onsomeintraepithelialTcells,andatlowerlevelsonearlyhematopoieticstemcellsinbonemarrow.
ThemouseCD90.2antibodydoesnotcross-reactwithCD90.1(Thy1.1).

Downstreamapplications

TcellsisolatedwithCD90.2MicroBeadswereusedtoanalyzecytokineexpressioninamousemodeloflungfibrosis1orafteradoptivetransferofTcellsfromwildtypeandknock-outmiceintoimmunodeficientmice.2FurThermore,CD90.2MicroBeadswereusedfortheisolationoftumor-infiltratingTcellstoevaluatetheirimmunotherapeuticpotential3orfunctionalproperties.4

Columns

Forpositiveselection:MS,LS,XS,orautoMACS®Columns.Fordepletion:LD,CS,D,orautoMACSColumns.
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