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Bpsbioscience/HSP70, His-tag/50287/200 µg

Species:Human
HostSpecies:E.coli
MW:71kDa
Genbank#:NM_005345
Tag(s):C-terminalHis-tag
a.a:2–641
Background:
Incooperationwithotherchaperones,Hsp70stABIlizespreexistentproteinsagainstaggregationandmediatethefoldingofnewlytranslatedpolypeptidesinthecytosolaswellaswithinorganelles.Thesechaperonesparticipateinalltheseprocessesthroughtheirabilitytorecognizenonnativeconformationsofotherproteins.Theybindextendedpeptidesegmentswithanethydrophobiccharacterexposedbypolypeptidesduringtranslationandmembranetranslocation,orfollowingstress-induceddamage.
Description:
HumanHeatShockProtein70(GenBankAccessionNo.NM_005345),a.a.2-641withC-terminalHis-tag,MW=71kDa,expressedinE.coli.
UniProt
P08107
Synonym(s):
HSP70,HeatShockProtein70,DnaK,HSP70i
Formulation:
40mMTris-HCl,pH8.0,110mMNaCl,2.2mMKCl,3mMDTT,20%glycerol,and200mMimidazole
Format:
Aqueousbuffersolution
Application(s):
Usefulforthestudyofenzymekinetics,screeninginhibitors,andselectivityprofiling.
Reference(s):
1.LeeK.J.etal.,Exp.Mol.Med.40(6),658-668(2008).
2.Birtas-AtesogluE.etal.,Clin.Exp.Rheumatol.26,S96-S98(2008).
Warning(s):
Avoidfreeze/thawcycles
ScientificCategory:
HeatShockProteins
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
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