CollagenVAlpha-1ChainN-propeptide-VRdomain(COL5A1)MonoclonalAntibody
CollagenValpha-1chainisaproteinthatinhumansisencodedbytheCOL5A1gene.Thisgeneencodesanalphachainforoneofthelowabundancefibrillarcollagens.Fibrillarcollagenmoleculesaretrimersthatcanbecomposedofoneormoretypesofalphachains.TypeVcollagenisfoundintissuescontainingtypeIcollagenandappearstoregulatetheassemblyofheterotypicfiberscomposedofbothtypeIandtypeVcollagen.ThisgeneproductiscloselyrelatedtotypeXIcollagenanditispossIBLethatthecollagenchainsoftypesVandXIconstituteasinglecollagentypewithtissue-specificchaincombinations.
MutationsinthisgeneareassociatedwithEhlers-Danlossyndrome,typesIandII.
ThisantibodyreactswithhumancollagenValpha-1chainpropeptide.Theepitoperecognizedisinthevariableregion.
Immunoblotting:useat1-5ug/ml.Immunohistochemistry:Formalin-fixed,paraffin-embeddedtissue,heat-inducedantigenretrieval.Useat1-10ug/ml.
Stainingofhumanskinwith#90009.
Thesearerecommendedconcentrations.Endusershoulddetermineoptimalconcentrationsfortheirapplications.
Reconstituteindistilledwater.
Thisproductisstableforatleastone(1)yearat-20oCto-70oC.Reconstitutedproductshouldbestoredinappropriatealiquotstoavoidrepeatedfreeze-thawcycles.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
SouthernBiotech/Goat Anti-Human Lambda-Alexa Fluor® 555/2070-32/1.0 mg
vectorlabs/Biotinylated Aleuria Aurantia Lectin (AAL)/B-1395/1 mg
vectorlabs/VECTASTAIN® Elite® ABC-HRP Kit (Peroxidase, Mouse IgG)/PK-6102/1 kit
vectorlabs/VECTASTAIN® Elite® ABC-HRP Kit (Peroxidase, Universal)/PK-6200/1 kit
vectorlabs/Unconjugated Musa Paradisiaca (Banana) Lectin (BanLec)/L-1410/5 mg
GiottoBiotech/Calmodulin N60D/5 mg/G02CLM60cn