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QED Bioscience/SMRT/56217/1 Ea


productdatasheet


SMRTMonoclonalAntibody


ORDERINGINFORMATION

CatalogNo.:56217

Size:100ugin10mMPBS,pH7.4.


BACKGROUND

SMRT(SilencingMediatorforRetinoidandThyroidreceptors)isa168kDnuclearprotein.Nuclearhormonereceptorsaretranscriptionfactorsregulatedbyligandbinding.Intheabsenceofligand,thereisaphysicalinteractionbetweenthenuclearreceptorsthatdonotinteractwithHsp90andafamilyofcorepressorswhichincludesSMRT.SMRThelpstargethistonedeacetylasesandothercomponentsofamultiproteinrepressorcomplextothespecifictargetpromotertosilencegenetranscription.


SPECIFICATIONSUMMARY

Antigen:AKLH-conjugatedsyntheticpeptidederivedfromhumanSMRTcorrespondingtoaa994-1005

HostSpecies:MouseStABIlizers:NonePreservatives:None.Availableonrequest.


SPECIFICITY

ThisantibodyrecognizeshumanSMRT.


APPLICATIONS

ImmunoblottingandImmuno-precipitation:useat1-5ug/ml.

Positivecontrol:HBL100


DILUTIONINSTRUCTIONS

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.


STORAGEANDSTABILITY

Thisantibodyisstableforatleastone

(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.


Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.


QEDBioscience,Inc.10919TechnologyPlace,SuiteC

SanDiego,CA92127

TollFree800.929.2114

Phone858.675.2405

Fax858.592.1509

info@qedbio.com

Visitourwebsiteforadditionalproductinformationandtoorderonline.

qedbio.com

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