ReliaTech/Mouse AntiHuman NKp80/101M588/100 µg

Clone/ABfeature:

(#7D32)

Antibodygeneration:

Thisantibodywasproducedfromahybridoma(mousemyelomafusedwithspleencellsfromamouse)immunizedwithextracellulardomainofhumanrecombinantproteinofNKp80,alsocalledkillercelllectin-likereceptorsubfamilyF,member1(KLRF1).

Antigen:

recombinanthumanNKp80

Stability:

Lyophilizedsamplesarestablefor2yearsfromdateofreceiptwhenstoredat-70°C.Reconstitutedantibodycanbealiquotedandstoredfrozenat< -20 °C for at least for six months without detectable loss of activity.

Reconstitution:

Reconstitutetheantibodywith500µlsterilePBSandthefinalconcentrationis200µg/ml.

Description:

NKp80,alsoknownaskillercelllectin-likereceptorsubfamilyF,member1(KLRF1),isatypeIItransmembraneproteinwithaC-typelectindomaininitsextracellularregion.NKp80isexpressedatthecellsurfaceofvirtuallyallNKcellsasadimerofapproximately80kDa.Ithasbeenshowntofunctionasaco-receptorwithnaturalcytotoxicityreceptors(NCR)toinduceactivationofNKcell-mediatedcytolysis.