ReliaTech/Goat AntiHuman NT4/102P198G/100 µg

Antibodygeneration:

Producedfromseraofgoatspre-immunizedwithhighlypure(>98%)recombinanthNT-4.Anti-hNT-4specificantibodywaspurifiedbyaffinitychromatographyemployingimmobilizedhNT-4matrix.

Antigen:

RecombinantHumanNT-4

Stability:

Thelyophilizedantibodyisstableforatleast2yearsfromdateofreceiptat-20°C.Thereconstitutedantibodyisstableforatleasttwoweeksat2-8°C.Frozenaliquotsarestableforatleast6monthswhenstoredat-20°C.

Reconstitution:

Reconstituteinsterilewatertoaconcentrationof0.1-1.0mg/mL.

Description:

llyrelatedtoβ-NGF,BDNF,andNT-3.Theseproteinsbelongtothecysteine-knotfamilyofgrowthfactorsthatassumestabledimericstructures.NT-4isexpressedintheprostate,thymus,placentaandskeletalmuscle.NT-4cansignalthroughtheLNGFRandtrkBreceptorsandpromotesthesurvivalofperipheralsensorysympatheticneurons.RecombinanthumanNT-4isanoncovalentlylinkedhomodimer,oftwo14.0kDapolypeptidemonomers(260totalaminoacidresidues).