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ReliaTech/Human BMP2/200002S/10 µg

Stability:

Lyophilizedsamplesarestableforgreaterthansixmonthsat-20°Cto-70°C.ReconstitutedBMP-2shouldbestoredinworkingaliquotsat-20°C.Avoidrepeatedfreeze-thawcycles!

Reconstitution:

ThelyophilizedBMP-2isbestsolublein50mMaceticacidataconcentrationof0.1mg/mlbutshouldbealsosolubleinmostaqueousbufferswhenthepHisbelow6.0.

Description:

HumanBoneMorphogeneticProtein-2(BMP-2)isadisulfide-bondedhomodimericproteinwithanapparentmolecularweightof26kDa.BMP-2regulatessimilarlytoitsnearesthomologueBMP-4diversefundamentalprocessesduringembryonicdevelopment:BMP-2andotherBMPproteinshavegreatpotentialformedicaltherapeuticapplications,inparticularbecausetheyalloworatleastacceleratetheossificationofextensivebonelesions.TheaminoacidsequenceofrecombinanthumanBMP-2startswithMQAKHKQ(position283)containingtheMetfromtheE.coliexpressionvector.BMP-2isaheparinbindingprotein.

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