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TOKU-E/Artesunate/A096/100 mg

Artesunateisananti-malarialdrugandhasbeenfoundtobeeffectiveagainstmultidrug-resistantPlasmodiumfalciparumandP.vivaxmalaria.Artesunatehasalsobeenfoundtohaveanti-canceractivityagainstleukemiaandcoloncancercelllines.

    CASNumber

    88495-63-0

    MolecularFormula

    C19H28O8

    MolecularWeight

    384.42

    MechanismofAction

    ArtesunatecausesdoublestrandedbreaksinparasiteDNAwhichleadstoabuildupofintracellularreactiveoxygenspecies(ROS).

    StorageConditions

    ≤30°C

    Spectrum

    ArtesunateisactiveagainstPlasmodiumfalciparumandP.vivax.

Specifications:

    Form

    Powder

    Appearance

    Whitecrystallinepowder

    Source

    Artemisiaannua

    ImpurityProfile

    Singleimpurity:Notmorethan0.5%
    Totalimpurities:Notmorethan2.0%

    pH

    3.5-5.0

    MeltingPoint

    132°C-136°C

    OpticalRotation

    +4.5-+6.5

    Assay

    (HPLC,Ondriedbasis):98.0%-102.0%

    LossonDrying

    Notmorethan0.5%

    ResidueOnIgnition

    Notmorethan0.1%

    HeavyMetals

    Notmorethan20ppm

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