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TOKU-E/Umirolimus/U008/1 mg

Umirolimus is a semi-synthetic macrocyclic lactone prepared from rapamycin by selective alkylation of the 42-hydroxy group, providing one of most hydrophobic tacrolimus analogues. Umirolimus has been targeted for use in stents and medical devices to suppress localised immunoreaction. Umirolimus is extensively cited in the literature with over 70 citations.

Umirolimus is soluble in ethanol, methanol, DMF and DMSO.

    CAS Number

    851536-75-9

    Molecular Formula

    C55H87NO14

    Molecular Weight

    986.3

    Mechanism of Action

    Umirolimus binds to receptor protein, FKBP12. The complex then binds to mTOR and prevents it from interacting with target proteins.

    Storage Conditions

    -20°C

Specifications:

    Appearance

    White solid

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