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Abbiotec/MEK1 (Thr292) Antibody/252555/0.1 ml188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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Abbiotec/MEK1 (Thr292) Antibody/252555/0.1 ml

MEK1(MAPKK1)catalyzestheconcomitantphosphorylationofathreonineandatyrosineresidueinaThr-Glu-TyrsequencelocatedinMAPkinases.MEKI(MAPKK1)activatesERK1andERK2MAPkinases,enzymeswhichareinvolvedinnumeroussignaltransductionpathways.DefectsinMEK1(MAPKK1)areacauseofcardiofaciocutaneoussyndrome(CFCsyndrome),alsoknownascardio-facio-cutaneoussyndrome.CFCsyndromeischaracterizedbyadistinctivefacialappearance,heartdefectsandmentalretardation.ThesitesonMEK1thatarephosphorylatedbyMAPkinaseareThr292andThr386.
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