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Abbiotec/LRFN4 Antibody/254039/0.1 mg188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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Abbiotec/LRFN4 Antibody/254039/0.1 mg

LRFN4isoneofafamilyoffivetransmembraneglycoproteinsthatarehighlyexpressedinneuronaltissues.LRFNproteinsshareleucine-richrepeat(LRR)-immunoglobulin-like(Ig)-fibronectintypeIII(Fn)-transmembranedomainstructurewithothermembersoftheLRR-Ig-FnproteinsuperfamilysuchastheSlitrkfamilyofproteins.ExpressionofLRFN1,-3,and-4mRNAwasdetectedinembryonicneuronalcells,whileLrfn2andLrfn5expressionwasprimarilyrestrictedtomorematurecells.LRFN1,-2,and-4boundtoPDZdomainsofpostsynapticPSD95,re-distributingPSD95tothecellperiphery.IthasbeensuggestedthattheLrfnproteinsplayaroleinthedevelopingand/ormaturevertebratenervoussystem.AtleasttwoisoformsofLRFN4areknowntoexist.Thisantibodyispredictedtonotcross-reactwithothermembersoftheLRFNfamily.
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