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Sciencell/Recombinant Rat IGF-1/145-01/1 Ea

Thisproductisforresearchuseonly.Itisnotapprovedforuseinhumans,animals,orinvitrodiagnosticprocedures.
TheIGFsaremitogenicpolypeptidegrowthfactorsthatstimulatetheproliferationandsurvivalofvariouscelltypesincludingmuscle,bone,andcartilagetissueinvitroviastimulatingtheuptakeofglucose,fattyacidsandaminoacids.TheliverpredominantlyproducesIGFs,althoughavarietyoftissuesproducetheIGFsatdistinctivetimes.TheIGFsbelongtotheinsulingenefamily,whichalsocontainsinsulinandrelaxin.TheIGFsaresimilarbystructureandfunctiontoinsulin,buthaveamuchhighergrowth-promotingactivitythaninsulin.IGF-IbindstoTypeIIGFreceptor,ahomologoftheinsulinreceptor.

Specifications:

CatalogNo.145-01
CountryofManufactureUnitedStates
ProductCoderrIGF-I
Size/Quantity10μg
ProductUseThisproductisforresearchuseonly.Itisnotapprovedforuseinhumans,animals,orinvitrodiagnosticprocedures.
StorageStoreat-20°Cafterreceiving.UponReconstitution,storeat2-8°Cforuptooneweek.FormaximalstABIlity,aliquotandstoreat-20°C.Avoidrepeatedfreeze/thawcycles.
ShippingInfoDryice
SynonymsIGF1,IGF-1,IGFI,SomatamedinC
AASequenceGPETLCGAELVDALQFVCGPRGFYFNKPTGYGSSIRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPTKSA
SourceEscherichiacoli
MolecularWeightApproximately7.6kDa,asinglenon-glycosylatedpolypeptidechaincontaining70aminoacids.
Purity>95%bySDS-PAGEandHPLCanalyses.
BIOLOGicalActivityFullybiologicallyactive.TheED50is
PhysicalAppearanceWhitelyophilizedpowder.
FormulationLyophilizedfroma0.2μmfilteredconcentratedsolutionin20mMPBS,pH7.0.
Endotoxin
ReconstitutionReconstituteinsteriledistilledwatercontaining0.1%BSAtoaconcentrationof0.1-1.0mg/mL.
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