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Lee Biosolutions/Cancer Antigen 72-4 (CA 72-4)/151-24-10/2 x 5 kU

Description
Product Name Cancer Antigen 72-4
Source Human Liver Metastases
Catalogue Number 151-24
Purity > 90% (SDS-PAGE)
Form Liquid
Activity > 100 kU/mL
Form Liquid in phosphate buffered saline, pH 7.4 with sucrose and 0.05% sodium azide
Appearance Clear and colorless
Recertification 2 years
Storage -20°C
Synonyms CA 72-4, Cancer Antigen 72-4, Cancer Antigen Tag-72
Unit Definition 51131907
Applications
Controls / Calibrators / Standards Immunoassays Clinical Chemistry Assay Development / Validation Life Science Tumor Markers
Overview

Lee Biosolutions is the leading producer and supplier of Cancer Antigen 72-4 (CA 72-4) for malignant diseases such as carcinomas of the pancreas, stomach, colon and ovaries.

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Elevated CA 72-4 levels in serum and plasma have been reported in various malignant diseases including carcinomas of pancreas, stomach, gallbladder, colon, ovaries, cervix and endometrium. The highest diagnostic sensitivities, according to current studies, are found for carcinomas of the gastrointestinal tract and ovaries.

Although some benign diseases such as rheumatic diseases or ovary cysts may also result in elevated levels of CA 72-4, clinical studies demonstrated diagnostic specificity of more than 95% for gastrointestinal and ovarian malignancies. There is a good correlation between CA 72-4 levels and tumor stage and size.

CA 72-4 is the marker of choice for the therapeutic monitoring and follow-up care of gastrointestinal cancer patients. Suitable second markers are CA 19-9 or CEA. It has been used as an independent marker for the therapeutic monitoring and follow-up care of ovarian cancer patients, in particular in CA 125 negative patients.

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