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LKT/KB NB 142-70/K0652/25 mg

ProductIDK0652
CasNo.1233533-04-4
Purity≥98%
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

KbNB142-70isaninhibitorofPKDthatisusedtostudyPKDactivityinresearchmodels.KbNB142-70preventsangiotensinII-inducedphosphorylationofhistonedeacetylasesandincreasesactivationofAktinintestinalepithelialcells.Thiscompoundmayalsoinhibitmigrationofintestinalepithelialcells.

ProductInfo

CasNo.

1233533-04-4

Purity

≥98%

Formula

C11H9NO2S2

FormulaWt.

251.32

IUPACName

9-Hydroxy-3,4-dihydro[1]benzothieno[2,3-f][1,4]thiazepin-5(2H)-one

ShippingandStorage

StoreTemp

-20°C

ShipTemp

Ambient

Downloads

InfoSheet

K0652InfoSheetPDF

References

Sinnett-SmithJ,NiY,WangJ,etal.ProteinkinaseD1mediatesclassIIahistonedeacetylasephosphorylationandnuclearextrusioninintestinalepithelialcells:roleinmitogenicsignaling.AmJPhysiolCellPhysiol.2014May15;306(10):C961-71.PMID:24647541.

NiY,Sinnett-SmithJ,YoungSH,etal.PKD1mediatesnegativefeedbackofPI3K/AktactivationinresponsetoGprotein-coupledreceptors.PLoSOne.2013Sep9;8(9):e73149.Erratumin:PLoSOne.2014;9(1).PMID:24039875.

YoungSH,RozengurtN,Sinnett-SmithJ,etal.RapidproteinkinaseD1signalingpromotesmigrationofintestinalepithelialcells.AmJPhysiolGastrointestLiverPhysiol.2012Aug1;303(3):G356-66.PMID:22595992.

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