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LKT/P55-TNFR PEPTIDE/P0055/5 mg

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Description

P55-TNFRisapeptidefragmentoftheP55tumornecrosisfactor(TNF)receptor.Thisreceptorisinvolvedininsulinsensitivity,celldeathsignaling,andthedevelopmentofatherosclerosis.P55-TNFRalsomediatesinflammatorysignalingandTcellproliferation.

ProductInfo

Purity

≥95%

Formula

C57H95N15O22

FormulaWt.

1342.48

ShippingandStorage

StoreTemp

-20°C

ShipTemp

Ambient

Downloads

InfoSheet

P0055InfoSheetPDF

References

XanthouleaS,ThelenM,PöttgensC,etal.Absenceofp55TNFreceptorreducesatherosclerosis,buthasnomajoreffectonangiotensinIIinducedaneurysmsinLDLreceptordeficientmice.PLoSOne.2009Jul7;4(7):e6113.PMID:19582157.

PandeyM,TuncmanG,HotamisligilGS,etal.Divergentrolesforp55andp75TNF-alphareceptorsintheinductionofplasminogenactivatorinhibitor-1.AmJPathol.2003Mar;162(3):933-41.PMID:12598326.

HillGR,TeshimaT,RebelVI,etal.Thep55TNF-alphareceptorplaysacriticalroleinTcellalloreactivity.JImmunol.2000Jan15;164(2):656-63.PMID:10623807

UysalKT,WiesbrockSM,HotamisligilGS.Functionalanalysisoftumornecrosisfactor(TNF)receptorsinTNF-alpha-mediatedinsulinresistanceingeneticobesity.Endocrinology.1998Dec;139(12):4832-8.PMID:9832419.

ShenY,LiR,ShiosakiK.Inhibitionofp75tumornecrosisfactorreceptorbyantisenseoligonucleotidesincreaseshypoxicinjuryandbeta-amyloidtoxicityinhumanneuronalcellline.JBiolChem.1997Feb7;272(6):3550-3.PMID:9013604.

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