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Human CD270 (Herpes Virus Entry Mediator, TNFRSF14, ATAR, LIGHTR, TR2) is a 36kd type I membrane protein that has been found on a broad range of lymphoid tissues. Its ligands include the TNF Ligand family members LTalpha and LIGHT, and the CD28/Ig Superfamily member BTLA(2).
Isotype: Murine IgG2a Kappa
Immunogen: Recombinant human CD270(HVEM)
Specificity: Antibody ANC3B7 is reactive with recombinant CD270 in EIA, and binds to CD270 present on human U-937 cell surface in Flow Cytometry.
References:
1) Hsu H, et al. (1997) J Biol Chem 272:13471.
2) Gonzalez LC, et al. (2005) PNAS 102(4): 1116-1121.
3) Laszlo G Radvany, Patrick Hwu, et al. (Dec 2012) Clin Cancer Res 18: 6758.
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