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CHROMOGENIX/APC Resistance determination due to Factor V Leiden mutation/4x2 ml/82 3120 63

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- Haemostasis Kits
  - APC-R
  - APCR-V
    - COATEST^®...
    - COATEST^®...
  - Protein C - Protein S
  - Factor VII
  - Factor VIII
  - Heparin
- Calibrators & Controls
- Bio-Reagents
- Chromogenic Substrates

High discrimination between genotypes with 100% sensitivity for FV:Q506. Reduces need for PCR determination. Applicable to anticoagulant treated patients.

COATEST^® APC^TM RESISTANCE V

An APTT-based kit for screening of factor V-related APC resistance. The high sensitivity and specificity of the test for the factor V:Q506 mutation is obtained by prediluting the sample plasma with an excess of V-DEF Plasma. The test design makes it possible to discriminate between heterozygous and homozygous factor V genotypes. It also allows for analysis of plasma from patients on heparin or oral anticoagulant therapy.

Measurement Principle

One volume of plasma is prediluted with four volumes of V-DEF Plasma. The dilution is then incubated with the APTT reagent for a standard period of time. Coagulation is triggered by the addition of CaCl2 in the absence and presence of exogenous APC and the time for clot formation is recorded.

Reagents and their stability when opened

APC/CaCl₂

4x2 ml

5 days

2-8°C

8 hours

15-25°C

APTT reagent

1x16 ml

1 week

15-25°C

1 month

2-8°C

CaCl₂

1x8 ml

1 month

2-8°C

1 week

15-25°C

V-DEF Plasma

4x4 ml

8 hours

15-25°C

24 hours

2-8°C

3 months

-20°C

APC/CaCl₂

4x2 ml

3 months

-20°C

Control Plasma Level 1

1x1 ml

6 hours

2-25°C

3 months

-20°C

Control Plasma Level 2

1x1 ml

6 hours

2-25°C

3 months

-20°C

Determinations

80-160

Part Number: 82 3120 63

COATEST^® APC^TM RESISTANCE V-S

Measurement Principle

Reagents and their stability when opened

V-DEF Plasma

2x4 ml

8 hours

15-25°C

24 hours

2-8°C

3 months

-20°C

CaCl₂

2x2 ml

1 week

15-25°C

1 month

2-8°C

APTT reagent

2x4 ml

1 week

15-25°C

1 month

2-8°C

APC/CaCl₂

2x2 ml

8 hours

15-25°C

5 days

2-8°C

3 months

-20°C

Control Plasma Level 1

1x1 ml

6 hours

2-25°C

3 months

-20°C

Control Plasma Level 2

1x1 ml

6 hours

2-25°C

3 months

-20°C

Determinations

40-80

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CHROMOGENIX/APC Resistance determination due to Factor V Leiden mutation/4x2 ml/82 3120 63

COATEST^® APC^TM RESISTANCE V

Measurement Principle

Reagents and their stability when opened

Determinations

Part Number: 82 3120 63

COATEST^® APC^TM RESISTANCE V-S

Measurement Principle

Reagents and their stability when opened

Determinations

Part Number: 82 3138 63

对照品标准品，生物试剂盒，gibco胎牛血清，试剂采购网，中国试剂网，细胞因子试剂盒

CHROMOGENIX/APC Resistance determination due to Factor V Leiden mutation/4x2 ml/82 3120 63

COATEST® APCTM RESISTANCE V

Measurement Principle

Reagents and their stability when opened

Determinations

Part Number: 82 3120 63

COATEST® APCTM RESISTANCE V-S

Measurement Principle

Reagents and their stability when opened

Determinations

Part Number: 82 3138 63

COATEST^® APC^TM RESISTANCE V

COATEST^® APC^TM RESISTANCE V-S