产品资料

immusmol/L-Tryptophan antibody (mouse monoclonal)/50µL (approx. 40 tissue sections)/IS011

Product overview

Product name	L-Tryptophan antibody
Synonyms	Anti-L-Trp antibody (S)-2-Amino-3-(3-indolyl)propionic acid antibody L-alpha-Amino-3-indolepropionic acid antibody (S)-2-Amino-3-(3-indolyl)propanoic acid antibody L-alpha-Amino-3-indolepropanoic acid antibody
Immunogen	Conjugated L-Tryptophan
Isotype	IgG1 k chain
Specificity	When tested in competitive ELISA, the anti-conjugated L-Tryptophanantibody did not show any significant cross reactivity with Tryptophananalogs, including Tryptamine
Volume	50µL
Lot number	140201

Storage

Form	Liquid
Purity	Purified IgG
Storage	Store at +4°C for short term (1-2 months). Aliquot and store at -20°C for long term. Avoid repeated freeze / thaw cycles.
Material safety datasheet	Download MSDS

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Protocols

IF - Cell cultures, Whole mounts, Tissue sections	Dilute antibody with the antibody diluent provided in the STAINperfect immunostaining kit A. Use at 1/250 -1/1000 dilution. Follow the STAINperfect protocol suited to your sample
Comments	Optimal working dilutions must be determined by the end-user
Restrictions	For research use only
Full protocol	Download STAINperfect protocol for dopamine staining
Protocols-at-a-glance


Complete Instructions for Use	Protocol-at-a-glance for cell cultures	Protocol-at-a-glance for whole mounts	Protocol-at-a-glance for tissue sections

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References

Antibody not yet cited. Submit an article and get a 10% discount.

Selected articles on L-Tryptophan:

Berthon C, Fontenay M, Corm S, Briche I, Allorge D, Hennart B, Lhermitte M, Quesnel B. Metabolites of tryptophan catabolism are elevated in sera of patients with myelodysplastic syndromes and inhibit hematopoietic progenitor amplification. Leuk Res. 2013 May;37(5):573-9. doi: 10.1016/j.leukres.2013.02.001. Epub 2013 Feb 28.

Schwarcz R, Bruno JP, Muchowski PJ, Wu HQ. Kynurenines in the mammalian brain: when physiology meets pathology. Nat Rev Neurosci. 2012 Jul;13(7):465-77. doi: 10.1038/nrn3257.

Pilotte L, Larrieu P, Stroobant V, Colau D, Dolusic E, Frédérick R, De Plaen E, Uyttenhove C, Wouters J, Masereel B, Van den Eynde BJ. Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase. Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2497-502. doi: 10.1073/pnas.1113873109. Epub 2012 Jan 30.

Hoshi M, Matsumoto K, Ito H, Ohtaki H, Arioka Y, Osawa Y, Yamamoto Y, Matsunami H, Hara A, Seishima M, Saito K. L-tryptophan-kynurenine pathway metabolites regulate type I IFNs of acute viral myocarditis in mice. J Immunol. 2012 Apr 15;188(8):3980-7. doi: 10.4049/jimmunol.1100997. Epub 2012 Mar 14.

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