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Discovery Antibodies/DMAB-anabaseine dihydrochloride/10 mg/D-110-10 mg188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品

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产品资料

Discovery Antibodies/DMAB-anabaseine dihydrochloride/10 mg/D-110-10 mg

Cat #: T-120

Alternative Name Mydriacyl^®

Lyophilized Powder

Bioassay Tested

Source Synthetic

MW: 284.3

Purity: >96%

Effective concentration 10 nM - 100 µM.

Structure - +

Chemical name N-Ethyl-3-hydroxy-2-phenyl-N-(pyridinylmethyl)propanamide.

Molecular formula C₁₇H₂₀N₂O₂.

CAS No.: 1508-75-4.

Activity Tropicamide is a muscarinic receptor (mAChR) antagonist, which shows a 3 fold selectivity for M4 over other muscarinic receptors^1-2. Tropicamide inhibits porcine intravesical ureter contraction with pIC₅₀ of ~7.5³.

References-Activity - +

Shipping and storage Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.

Solubility DMSO. Centrifuge all product preparations before use (10000 x g 5 min).

Storage of solutions Up to four weeks at 4°C or three months at -20°C.

Our bioassay - +

References - Scientific background

1. Bonner, T.I. et al. (1989) Trends. Neurosci. 12, 148.

2. Felder, C.C. et al. (1995) FASEB. J. 9, 619.

3. Bonner, T.I. et al. (1987) Science 237, 527.

4. Peralta, E.G. et al. (1987) EMBO J. 6, 3923.

5. Bonner, T.I. et al. (1988) Neuron 1, 403.

6. Liao, C.F. et al. (1989) J. Biol. Chem. 264, 7328.

7. Liao, C.F. et al. (1989) J. Biol. Chem. 264, 7328.

8. Lazareno, S. et al. (1990) Br. J. Pharmacol. 109, 1120.

9. Hernandez, M. et al. (1993) Br. J. Pharmacol. 110, 1413.

10. Manny, R.E. et al. (2001) Invest. Ophtalmol. Vis. Sci. 42, 1728.

Scientific background - +

Target M1-M5 muscarinic receptors

Lyophilized Powder

Click here to receive a 250 mg free trial sample!

Last update: 26/09/2019

Tropicamide (#T-120) is a highly pure, synthetic, and biologically active compound.

For research purposes only, not for human use