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Bpsbioscience/Bromodomain NonAcetylated Ligand 3/33009/0.5 ml @ 20 µM
Background:
Bromodomainsfunctionasacetyl-lysinebindingdomains,andbromodomain/acetyl-lysinerecognitioncanregulatehistonemodification,DNAreplications,chromatinremodeling,andgenetranscription.
Description:
TheBromodomainNon-acetylatedLigand3isacontrolpeptidefortheacetylatedBromodomainLigand3,Cat.#33008.ItisderivedfromhistoneH3andcontainsaC-terminalGGlinker,followedbyabiotinylatedLys.ThispeptideissuitableforuseasanegativecontrolligandforbromodomainsincludingTRIM24.
Purity:
≥95%
SuppliedAs:
20µMaqueoussolution
Concentration:
20µM
Format:
Aqueousbuffersolution
Storage/Stability:

Atleast6monthsfromdateofreceipt,whenstoredasdirected

Application(s):
Usefulasanegativecontrolforthestudyofbromodomainbindingassays,screeninginhibitors,andselectivityprofiling.
Reference(s):
Muller,S.,etal.ExpertRev.Mol.Med.2011Sep13;13:e29.
Warning(s):
Avoidfreeze/thawcycles.
ScientificCategory:
Bromodomain
ProductType:
Substrate
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