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Genemay/Mouse anti-Human CD11a, PE Conjugated mAb./GMH011P/25 Tests

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CatalogNo./Size:GMH011P-025/25Tests
GMH011P-100/100Tests
Vol.per.Test:10μl/Test
Clone:TS1/22.1.1.13
Isotype:MouseIgG1
Reactivity:Human,Notyettestedinotherspecies.
Workshop:N/A
StorageBuffer:Phosphate-bufferedsolution,pH7.4,containing0.09%sodiumazideand0.2%(w/v)BSA
StorageCondition:Storeat4�C.DONOTFREEZE.LIGHTSENSITIVEMATERIAL.
Applications:FlowCytometry
ApplicationsNotes:

FACS:Use10µlfor106cells

NormalhumanperipheralbloodlymphocytesanalyzedwithPECD11a(TS1/22.1.1.13)mAb.

Description:

TS1/22.1.1.13reactswithCD11a,a180kDamolecule.CD11aistheachainoftheleukocytefunctionassociatedantigen-1(LFA-1a),andisexpressedonallleukocytesincludingTandBcells,monocytes,andgranulocytes,butisabsentonnon-hematopoietictissueandhumanplatelets.CD11/CD18(LFA-1),amemberoftheintegrinsubfamily,isaleukocyteadhesionreceptorthatisessentialforcell-to-cellcontact,suchaslymphocyteadhesion,NKandT-cellcytolysis,andT-cellproliferation.CD11/CD18isalsoinvolvedintheinteractionofleucocyteswithendothelium.
*CD11aantibodyhasbeenusedtoreducesgraftfailureforbonemarrowgraftsinimmunodeficientchildren.
Thiscloneiscrossreactivewithnon-humanprimate.