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LifeSensors/UB219-3 NMOLES UBE2T/UB219-3 NMOLES UBE2T

UBE2Tcanmediatethetransferofubiquitinfromubiquitin-activatingenzymeE1toasubstrateproteinorE3ligase.ThisE2enzymehasbeenshowntobeessentialfortheFanconianemiapathway.UBE2TconjugatingactivityisinvolvedwiththemonoubiquitylationofFANCD2,co-functioningwiththeE3ligaseFANCL.


Info


Amount3nmol
StateLiquid
MolecularWeight22,520.9Da
SourceHumanRecombinant
FusionTagNone
AccessionNumberQ9NPD8
AlternateNamesHSPC150,PIG50
Storage-80°C,avoidfreeze/thawcycles
StABIlity1yearunderrecommendedstorageconditions
RecommendedUseEnzymeconcentrationof100nM–1mMisrecommendedfor invitro conjugation.



Applications

  • IdentifycognateE2/E3pairs
  • Characterizeupregulation/downregulationofE2enzymes
  • Buildpoly-ubiquitinchains
  • CharacterizeubiquitinchainspecificityofE2enzymes
  • AnalyzeexpressionofE2enzymes


Benefits

  • Untagged(native)E2conjugationenzyme


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