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Neuromics/NMDA Receptor 2B/RA25063/10 ug

Type:RabbitIgG

 

Applications:IHC;WB;IP

E=ELISA;FACS;FC=FlowCytometry;FPLC=FastProteinLiquidChromatography;GF=GravityFlow;HPLC=HighPerformanceLiquidChromatography;ICC=Immunocytochemistry;IF=Immunofluorescence;IHC=Immunohistochemistry;IP=Immunoprecipitation;NAC=Non-adherentCellAssays;NB=NeutralizationofBioactivity;SE=SandwichELISA;TPE=TargetedProteinExpression;WB=Westernblotting;;AC=AdherentCellAssays;FM=FluorescentMicsroscopy;;;BSC-CM5=BiacoreSensorChipCM5;BSM=BiosactiveSmallMoleculeorPeptide;CDM=CellDifferentiationMedia;;;;;;HealthandFitness;;;DNAExtraction/Purification;;InvivoLikeAssays

SpeciesReactivity:H;M;R

B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;All

Format:AffinityPurified-liquid

 

Immunogen:C-terminalfusionproteinrepresentingaminoacids1253-1391ofratNMDAR2B.

 

Picture

Theionchannelsactivatedbyglutamatearedividedintotwoclasses.ThosethataresensitivetoN-methyl-D-aspartate(NMDA)aredesignatedNMDAreceptors(NMDAR)whilethoseactivatedbykainateanda-amino-3-hydroxy-5-methyl-4-isoxalonepropionicacid(AMPA)areknownaskainate/AMPAreceptors(K/AMPAR).NMDAreceptorsareamongthemoststudiedreceptorsinneurosciencebecausetheyareinvolvedinneuronalcelldevelopmentandplasticity,acellularcorrelateforlearning.NMDAreceptorsarealsoimplicatedinseveraldisordersofthecentralnervoussystemincludingepilepsyandischemicneuronalcelldeath.NMDAreceptorsalsoappeartobeatargetforethanolatphysiologicalconcentrationsandthereforemayplayasignificantroleinalcoholism.

Image:  NMDAReceptor2BWesternBlot:RatHippocampus.

RelatedReagentstoConsider:

NMDAReceptor1,N1

NMDAReceptor2A

NMDANR1Pan

phospho-NMDAReceptor1(Ser890)

Phospho-NMDAReceptor1(Ser896)

mGluRandGluRs

GABAReceptors

AllNeurotransmissionResearchAntibodies

Neuron/GlialMarkers

PrimaryNeuronsandAstrocytes


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