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Neuromics/TP63/TP73L/GT15189/100 ug

Type:GoatIgG

 

Applications:ICC;WB;E

E=ELISA;FACS;FC=FlowCytometry;FPLC=FastProteinLiquidChromatography;GF=GravityFlow;HPLC=HighPerformanceLiquidChromatography;ICC=Immunocytochemistry;IF=Immunofluorescence;IHC=Immunohistochemistry;IP=Immunoprecipitation;NAC=Non-adherentCellAssays;NB=NeutralizationofBioactivity;SE=SandwichELISA;TPE=TargetedProteinExpression;WB=Westernblotting;;AC=AdherentCellAssays;FM=FluorescentMicsroscopy;;;BSC-CM5=BiacoreSensorChipCM5;BSM=BiosactiveSmallMoleculeorPeptide;CDM=CellDifferentiationMedia;;;;;;HealthandFitness;;;DNAExtraction/Purification;;InvivoLikeAssays

SpeciesReactivity:H

B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;All

Format:AffinityPurified-liquid

 

Immunogen:Purified,E.coli-derived,recombinanthumantumorprotein63(rhTP63;aa1-300;Accession#NP_003713).

 

Picture

Thispolyclonalanti-TP63ispredictedtorecognizeallisoformsofTP63,includingTAp63,DeltaNp63,TP63α,β,γ,andδ.TP63,alsonamedp63,TP73L,p51,p40orKET,wasoriginallyidentifiedasap53familymember.Itishighlyexpressedinembryonicectodermandinthenucleiofbasalregenerativecellsofmanyepithelialtissuesintheadultincludingskin,breastmyoepithelium,oralepithelium,prostateandurothelia.TheexpressionofvariousTP63isoformshasbeensuggestedtoplayaroleindevelopment,epithelialcellmaintenanceandtumorigenesis.1-3

1.Courtois,S. etal.,2004,Oncogene23(3):631-638.
2.Koster,M.I.andD.R.Roop,2004,J.Dermatol.Sci. 34(1):3-9.
3.Vincek,V. etal.,2003,AnticancerRes.23(5A):3945-3948.

 

 

 

 

Image:TP63staininginhumanSSC-25cellsusing.CellswerestainedusingRhodamineRed-conjugateddonkeyanti-goatsecondaryantibody.

OtherReagentstoConsider:

CancerAntibodies

CancerProteins

Stem CellReagents  


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