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Neuromics/MARCKS (Myristoylated Alanine Rich C Kinase Substrate)/RA22111/100 ul188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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Neuromics/MARCKS (Myristoylated Alanine Rich C Kinase Substrate)/RA22111/100 ul

Type:RabbitIgG

 

Applications:ICC;IF;WB

E=ELISA;FACS;FC=FlowCytometry;FPLC=FastProteinLiquidChromatography;GF=GravityFlow;HPLC=HighPerformanceLiquidChromatography;ICC=Immunocytochemistry;IF=Immunofluorescence;IHC=Immunohistochemistry;IP=Immunoprecipitation;NAC=Non-adherentCellAssays;NB=NeutralizationofBioactivity;SE=SandwichELISA;TPE=TargetedProteinExpression;WB=Westernblotting;;AC=AdherentCellAssays;FM=FluorescentMicsroscopy;;;BSC-CM5=BiacoreSensorChipCM5;BSM=BiosactiveSmallMoleculeorPeptide;CDM=CellDifferentiationMedia;;;;;;HealthandFitness;;;DNAExtraction/Purification;;InvivoLikeAssays

SpeciesReactivity:M;R

B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;All

Format:liquid

 

Immunogen:PurifiedrecombinantMARCKSprotein.

 

Picture
MARCKSisamajorproteinofbrain,andisconcentratedinsynapsesofneurons.Itappearstofunctioninsynapticvesiclecyclingandhasbeenshowntobindbothactinandcalmodulininvitro.MARCKSbelongstoafamilyofproteinswithsimilaractinandcalmodulinbindingproperties.DeletionoftheMARCKSgeneinmiceresultsinembryonicbraindefectsanddeath. It playsavitalroleinthenormaldevelopmentalprocessesofneurulation,hemispherefusion,forebraincommissureformation,andformationofcorticalandretinallaminations.

Image:Viewofmixedneuron/glialculturesstainedwithourMARCKSantibody(red)andMAP2madeinchicken.NotethattheMARCKSantibodystainsvesicularstructuresbothintheglialcellsandinthedendritesoftheneurons,whicharestronglystainedwiththeMAP2antibody.Protocol ondata-sheet.

MoreLinks:

MAP-2-AntibodyChicken

CalmodulinAntibody

CalciumSignalingAntibodies                              

AxonGrowthandGuidanceAntibodies

AxonGrowthandGuidanceProteins     

Neuron-GlialExpressedProteins                                   

Neuron/SynapseMarkers

PrimaryNeuronsandAstrocytes-Primaryhuman,ratandmouseneuronsandastrocytesbyCategory

StemCellResearchReagents

Picture[2]

Image:Westernblotofwholeratcortex(Co),cerebellum(Ce),brainstem(BS)andspinalcord(SC)homogenatestainedwithRPCA-MARCKS,atdilutionof1:10,000.AprominentbandrunningwithanapparentSDS-PAGEmolecularweightof~80kDacorrespondstoMARCKS.Protocol ondata-sheet.


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