
Synaptophysinisa38kDaglycoproteinpresentinthemembraneofneuronalpresynapticvesiclesinbrain,spinalcord,retina,vesiclesofadrenalmedulla,neuromuscularjunctions,andendocrinecells.Itisalsoexpressedbyneuroendocrinecellsthroughoutthebody,bothnormalandneoplastic.SynaptophysinisausefulMarkerfortheidentificationofnormalneuroendocrinecellsandneuroblatomas.
ItisalsosuspectedtoplayaroleinRespiratory Disorders (i.e.sleepapnea)andLewyBodyNeurodegenerativeDiseases.
SynaptophysinCustomerPublications/SeeCustomerDataforWesternBlot
CustomerTestimonial:"Thesynaptophysinantibodyworksverynice.WearecurrentlyusingittoverifymembranelocalizationofotherproteinsforIHC,andasamembranefractionloadingcontrolforwestern.Ithinkwewillhaveapublicationsentoutsoonusingit,Illletyouknow."CourtesyofDanHarrigan,MitchellLab,UW-Madison.