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Adipogen/PI103/SYN1065M001/1 mg
MoreInformation
ProductDetails
SynonymsPI-103
ProductTypeChemical
Properties
FormulaC19H16N4O3
MW348.4
CAS371935-74-9
PurityChemicals≥95%
AppearanceSolid.
SolubilitySolubleinDMSO.Slightlysoluble(<1mg l)="" in="" ethanol.="">
DeclarationManufacturedbySynKinase.
OtherProductDataTarget:PI3K-AKT-mTOR|KinaseGroup:LipidKinase|Substrate:Lipid

ClickhereforOriginalManufacturerProductDatasheet
Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet.
InChiKeyTUVCWJQQGGETHL-UHFFFAOYSA-N
ShippingandHandling
ShippingAMBIENT
ShortTermStorage+4°C
LongTermStorage-20°C
Use/StABIlityStableforatleast2yearsafterreceiptwhenstoredat-20°C.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
PI-103isanisoform-selectiveclassIPI3KandmTORinhibitor.Ithasactivityonp110α-δwithIC(50)valuesof2nM,3nM,3nM,15nMrespectively.ItislesspotentagainstmTORandDNA-PKwithIC(50)valuesof30nMand23nMrespectively.
ProductReferences
  1. AdualPI3kinase/mTORinhibitorrevealsemergentefficacyinglioma:Q.W.Fan,etal.;CancerCell9,341(2006)

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