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Adipogen/Streptochlorin/AGCN20141M001/1 mg

MoreInformation
ProductDetails
SynonymsSF2583A;12815A;4-Chloro-5-(3-indolyl)oxazole;3-(4-Chloro-5-oxazolyl)-1H-indole
ProductTypeChemical
Properties
FormulaC11H7ClN2O
MW218.6
CAS120191-51-7
Source/HostChemicalsIsolatedfromStreptomycesroseolilacinus.
PurityChemicals≥95%(HPLC)
AppearanceCrystallinesolid.
SolubilitySolubleinDMSOormethanol.Insolubleinwaterorhexane.
DeclarationManufacturedbyBioLinksK.K.withcourtesystrainfromTheKitasatoInstitute.
InChiKeyBKYJGKRXUHPPLR-UHFFFAOYSA-N
ShippingandHandling
ShippingAMBIENT
ShortTermStorage+4°C
LongTermStorage-20°C
HandlingAdviceKeepcoolanddry.
Use/StabilityStableforatleast2yearsafterreceiptwhenstoredat-20°C.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
  • Antibiotic[1].
  • TNF-α-inducedNF-κBactivationinhibitor[1].
  • Antiangiogenic[1].
  • Apoptosisinducer[2-4].
  • Anticancercompound.Selectivecytotoxicagainstseveralcancercelllines[2-4].
  • Tyrosinaseinhibitor[5].
ProductReferences
  1. Streptochlorin,amarinenaturalproduct,inhibitsNF-kappaBactivationandsuppressesangiogenesisinvitro:I.K.Choi,etal.;J.Microbiol.Biotechnol.17,1338(2007)
  2. Isolationandstructuredeterminationofstreptochlorin,anantiproliferativeagentfromamarine-derivedStreptomycessp.04DH110:H.J.Shin,etal.;J.Microbiol.Biotechnol.17,1403(2007)
  3. StreptochlorinisolatedfromStreptomycessp.inducesapoptosisinhumanhepatocarcinomacellsthroughareactiveoxygenspecies-mediatedmitochondrialpathway:D.Y.Shin,etal.;J.Microbiol.Biotechnol.18,1862(2008)
  4. InductionofapoptosisbystreptochlorinisolatedfromStreptomycessp.inhumanleukemicU937cells:C.Park,etal.;Toxicol.InVitro22,1573(2008)
  5. PhysicochemicalcharactersofatyrosinaseinhibitorproducedbyStreptomycesroseolilacinusNBRC12815:T.Nakashima,etal.;Biol.Pharm.Bull.32,832(2009)

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