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Adipogen/ER 17259406 hydrobromide/SYN3002M005/5 mg188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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Adipogen/ER 17259406 hydrobromide/SYN3002M005/5 mg
MoreInformation
ProductDetails
SynonymsAtopaxarhydrobromide;ER-172594-06;E5555
ProductTypeChemical
Properties
FormulaC29H39BrFN3O5.HBr
MW608.5.80.9
CAS474550-69-1
PurityChemicals≥95%
AppearanceSolid.
SolubilitySolubleinDMSO.
DeclarationManufacturedbySynKinase.
OtherProductDataTarget:N/A|KinaseGroup:N/A|Substrate:N/A

ClickhereforOriginalManufacturerProductDatasheet
Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet.
InChiKeyUNMBLVOFOAGGCG-UHFFFAOYSA-N
ShippingandHandling
ShippingAMBIENT
ShortTermStorage+4°C
LongTermStorage-20°C
Use/StabilityStableforatleast2yearsafterreceiptwhenstoredat-20°C.
Documents
MSDSNo
ProductSpecificationSheet
DatasheetDownloadPDF
E5555showspotentinhibitoryeffectsonhumanplateletaggregationinducedbythrombinandTRAPwithICvaluesof0.064and0.031µM,respectively.
ProductReferences
  1. Thein-vitroeffectsofE5555,aprotease-activatedreceptor(PAR)-1antagonist,onplateletbioMarkersinhealthyvolunteersandpatientswithcoronaryarterydisease:V.L.Serebruany,etal.;Thromb.Haemost.102,111(2009)
  2. Double-blind,placebo-controlledPhaseIIstudiesoftheprotease-activatedreceptor1antagonistE5555(atopaxar)inJapanesepatientswithacutecoronarysyndromeorhigh-riskcoronaryarterydisease:S.Goto,etal.;Eur.HeartJ.31,2601(2010)
  3. ThenovelandorallyactivethrombinreceptorantagonistE5555(Atopaxar)inhibitsarterialthrombosiswithoutaffectingbleedingtimeinguineapigs:M.Kogushi,etal.;Eur.J.Pharmacol.657,131(2011)

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