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Adipogen/Palbociclib isethionate/SYN1180AM100/100 mg188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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Adipogen/Palbociclib isethionate/SYN1180AM100/100 mg

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ProductDetails
SynonymsPD-0332991
ProductTypeChemical
Properties
FormulaC24H29N7O2.C2H6O4S
MW447.5.126.1
CAS827022-33-3
PurityChemicals≥95%
AppearanceSolid.
SolubilitySolubleinDMSOorethanol.
DeclarationManufacturedbySynKinase.
OtherProductDataTarget:Abl-CDK2-CDK4-CDK5-CDK7|KinaseGroup:PTK|Substrate:Tyrosine

ClickhereforOriginalManufacturerProductDatasheet
Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet.
InChiKeyLYYVFHRFIJKPOV-UHFFFAOYSA-N
ShippingandHandling
ShippingAMBIENT
ShortTermStorage+4°C
LongTermStorage-20°C
Use/StabilityStableforatleast2yearsafterreceiptwhenstoredat-20°C.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
PD0332991(Palbociclib)IsethionateistheisethionateofPD0332991,ahighlyspecificinhibitorofCDK4andCDK6withIC(50)valuesof11nMand16nM,respectively.ItshowsnoactivityagainstCDK1/2/5,EGFR,FGFR,PDGFR,InsR.
ProductReferences
  1. PD-0332991,apotentandselectiveinhibitorofcyclin-dependentkinase4/6,demonstratesinhibitionofproliferationinrenalcellcarcinomaatnanomolarconcentrationsandmolecularMarkerspredictforsensitivity:J.E.Logan,etal.;AnticancerRes.33,2997(2013)

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